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The double punch of perchlorate

To make thyroid hormones, which are critical in development, iodine ions (I−) must be transported into thyroid cells. This is achieved by the sodium ion (Na+)/I− symporter (NIS), which couples the energetically unfavorable import of one I− with the energetically favorable import of two Na+. NIS also transports the environmental pollutant perchlorate (ClO4−), but in…

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COVID-19 Update: Airborne Virus Debate, Stem Cells

Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Here are the coronavirus stories Medscape's editors around the globe think you need to know about today: Airborne Virus Controversy Hundreds of scientists have written a letter to the World Health Organization (WHO) outlining evidence that SARS-CoV-2 can spread through smaller,…

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Patients with colorectal cancer (CRC) who have peritoneal metastases should only be treated in a specialized referral center and given systemic chemotherapy before cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS-HIPEC), suggest the results of several new studies in this relatively rare patient population. The choice of intraperitoneal chemotherapy may not affect overall survival, with both…