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Neonatal SARS-CoV-2 May Present With Hypoxemia Without Respiratory Distress

(Reuters Health) - Neonatal SARS-CoV-2 infection may present in the first days of life with clinically significant hypoxemia in a newborn that doesn't have overt signs of respiratory distress or require oxygen therapy, one case report suggests. "In mild disease, there may be non-specific signs such as poor feeding that alert the care-providers, before signs…

SARS-CoV-2 Coronavirus Produces Long Tentacles in Infected Cells

Cells hijacked by SARS-CoV-2, a novel coronavirus that causes the COVID-19 disease, grow arm-like extensions, or filopodia, which may explain rapid viral spread throughout the body. SARS-CoV-2 viruses visible on a cell with filopodia. Image credit: Elizabeth Fischer, Miscroscopy Unit NIH / NIAID. “Viruses are unable to replicate and spread on their own: they need…

SARS-CoV-2-attacking T cells found in 10 COVID-19 patients and 2 uninfected controls

Patients suffering from severe respiratory symptoms as a result of SARS-CoV-2 infection can rapidly generate virus-attacking T cells, and can increase this production over time, suggests a new study of T cells from 10 COVID-19 patients under intensive care treatment. In addition, 2 out of 10 healthy individuals without prior exposure to the virus harbored…

Scientist map SARS-CoV-2 infection in cells of nasal cavity, bronchia, lungs

SARS-CoV-2 (red) infected ciliated cells in the COVID-19 patient's bronchi. Credit: Takanori Asakura, PhD, UNC School of Medicine In a major scientific study published in the journal Cell, scientists at the UNC School of Medicine and the UNC Gillings School of Global Public Health have characterized the specific ways in which SARS-CoV-2—the coronavirus that causes…

Serology for SARS-CoV-2: Apprehensions, opportunities, and the path forward

AbstractSerological testing for SARS-CoV-2 has enormous potential to contribute to COVID-19 pandemic response efforts. However, the required performance characteristics of antibody tests will critically depend on the use case (individual-level vs. population-level).Making data-driven decisions on how to fight the COVID-19 pandemic without completely shutting down economies will require better tools to understand the extent of…

Who is most likely to be infected with SARS-CoV-2?

Despite the daily updates on number of cases, hospital admissions, and deaths around the world and the increasing number of hospital-based case series, some of the fundamental information about how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spreads in the population and who is really at risk of both infection and severe consequences is still…

We do not know yet whether a mutation has actually made SARS-CoV-2 more transmittable

Evolving ideas — A mutation in the virus seems to be getting more common, but we don't know why. John Timmer - May 6, 2020 2:22 pm UTC Enlarge / YOGYAKARTA, INDONESIA - MAY 06: An Indonesian health official wearing a protective suit prepares test kits during a mass rapid test for COVID-19 amid the…

Presymptomatic SARS-CoV-2 Infections and Transmission in a Skilled Nursing Facility

22 References1 Citing ArticleAbstract BackgroundSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can spread rapidly within skilled nursing facilities. After identification of a case of Covid-19 in a skilled nursing facility, we assessed transmission and evaluated the adequacy of symptom-based screening to identify infections in residents. MethodsWe conducted two serial point-prevalence surveys, 1 week apart,…

SARS-CoV-2 may be exploiting our body immune system’s ‘first responder’ cells

Home News An illustration showing the SARS-CoV-2 virus binding to an ACE2 receptor on a human cell. (Image: © Shutterstock) The new coronavirus, known as SARS-CoV-2, may be using part of the human body's own immune response against us, a new study suggests.The novel coronavirus is known to use a keyhole called the ACE2 receptor…

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Half of Oklahoma ruled booking land by Supreme Court

Washington The United States Supreme Court on Thursday recognized about half of Oklahoma as Native American reservation land and overturned a tribe member's rape conviction because the location where the crime was committed should have been considered outside the reach of state criminal law.The justices ruled 5-4 in favor of a man named Jimcy McGirt…

Supreme Court: Trump can obstruct Congress, not DA, from tax records

Washington The Supreme Court on Thursday upheld the Manhattan district attorney's demand for President Donald Trump's tax returns, but kept a hold on Mr. Trump’s financial records that Congress has been seeking for more than a year.The outcome in the two cases is at least a short-term victory for Mr. Trump, who has strenuously sought…

Pentagon leaders to affirm on use of military throughout discontent

Washington The Pentagon's top leaders are going before Congress for the first time in months to face a long list of controversies, including their differences with President Donald Trump over the handling of protests near the White House last month during unrest triggered by the killing of George Floyd in police hands.The House hearing Thursday will provide the…

Latest Health News

KRASG12C-Mutant NSCLC Likely Smoking-Related, Targetable by Brain Metastasis Therapies

NEW YORK (Reuters Health) - KRASG12C-mutant non-small-cell lung cancer (NSCLC) appears to be smoking-related and is likely targetable by inhibitors that can delay or prevent brain metastasis, according to an analysis of real-world outcomes. "Currently, the majority of druggable oncogene-driven NSCLCs occur in non-smokers/light ex-smokers," Dr. Wanyuan Cui of the Peter MacCallum Cancer Centre in…

Proton Pump Inhibitors Tied to COVID-19 Risk

Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. People who use proton pump inhibitors (PPIs) may be more likely to get COVID-19, researchers say. In light of this finding, physicians should consider which patients truly need these powerful acid-lowering drugs, said Brennan Spiegel, MD, MSHS, professor of medicine and…

Breathed In Dye Enables Intraoperative Visualization of Lung-Tumor Margin

NEW YORK (Reuters Health) - Inhalational indocyanine green (ICG) can be useful for the intraoperative visualization of lung-tumor margin, researchers from South Korea report. Surgical resection with adequate tumor-free margin provides optimal long-term survival in patients with early-stage non-small-cell lung cancer (NSCLC), but defining the tumor margin during surgery can be challenging. Dr. Hyun Koo…